Professor John Mugler of UVA visit WIPM

In May 5th, 2016, Professor John Mugler of UVA visited WIPM at the invitation of Professor Xin Zhou of WIPM, and made the 10th Tianjuan Wang report named "Evaluation of Gas Uptake/Exchange in the Human Lung using Hyperpolarized ₁₂₉Xe: Experience at the university of Virginia".

John Mugler is the professor of Biomedical Engineering& Medical Imaging, University of Virginia and the associate editor of Magnetic Resonance in Medicine.and He is a internationally renowned expert in magnetic resonance imaging.His main research results are inviting 3D MP-Rage sequence which is widely used for 3D T1 weighted imaging, and developing 3D fast spin echo technique, the SPACE sequence, which is widely used in clinical. He published more than 200 papers in PNAS, Radiology, Magn Reson Med, etc, which were cited more than 7000 times.

During the report, Professor John Mugler briefly introduced the application of hyperpolarized gas in lung MRI, and the signal of hyperpolarized ₁₂₉Xe in lung. He detailed several common sequences like XTC, MXTC, CSSR, and the role of sequences played in the diagnosis of lung disease. Meanwhile, Professor John Mugler introduced the work of his group. They can discover the patients with COPD by simultaneously obtaining ventilation image and dissolved image of ₁₂₉Xe in lung. The group invited a new method named"accelerated ₁₂₉Xe spectroscopic imaging", and can simultaneously get ventilation image and dissolved image by 3D radial method, which can diagnosis lung diseases like COPD, asthma, idiopathic pulmonary fibrosis (IPF) and so on. Academician Chaohui Ye and Professor Xin Zhou attended the report and launched discussion with John Mugler. The report also aroused great interest all students. They asked some questions about his work.The report achieved good results.

After the report, Professor John Mugler visited the laboratory and had a in-depth communication with teachers and students. Besides, they discussed about the in-depth cooperation in the future.